Endocrine Abstracts

Alterations in (small) intestinal microbiota are associated with aberrant insulin secretion. We previously showed that fecal transplantation (infusing intestinal microbiota from lean donors) in insulin resistant subjects has beneficial effects on the recipients’ microbiota composition and glucose metabolism via altering fecal SCFA producers levels (Vrieze, Gastroenterology 2012). Followup studies suggest that this beneficial effect can be divided in responders and non res...

Alterations in (small) intestinal microbiota are associated with obesity and insulin resistance, with the latter usually characterized by low grade endotoxemia. We recently showed that fecal transplantation (infusing intestinal microbiota from lean donors) in male recipients with metabolic syndrome has beneficial effects on the recipients’ microbiota composition and glucose metabolism via lowering plasma endotoxin levels (Vrieze, Gastroenterology 2012). Moreover, prelimin...